- 20 Apr, 2022
- Charlotte Roughton
My Microbio22
My view of Microbio22 In December 2021, I opened quite a surprising email.
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Our C. difficile Structural Microbiology group focuses on detailed structural and functional characterisation of proteins involved in key pathogenicity pathways in this major human pathogen. We are particularly interested in Clostridioides difficile spores, the dormant, resistant cell forms that are the transmission vehicle, as well as surface proteins and their role in infection.
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Nature Communications, 2022
Abstract Many bacteria and archaea possess a two-dimensional protein array, or S-layer, that covers …
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Molecular Microbiology, 2018
Abstract Clostridium difficile remains the leading cause of antibiotic-associated diarrhoea in …
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Molecular Microbiology, 2016
Abstract Engulfment of the forespore by the mother cell is a universal feature of endosporulation.
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Anaerobe, 2019
Abstract Clostridioides difficile infection (CDI) continues to be a substantial healthcare burden, …
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Frontiers in Microbiology, 2017
Abstract Clostridium difficile remains a leading nosocomial pathogen, putting considerable strain on …
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Acta Cryst D76, 2020
Abstract Many biologists are now routinely seeking to determine the three-dimensional structures of …
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My view of Microbio22 In December 2021, I opened quite a surprising email.
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Solving the C. difficile’s armour - while developing my own About me In November 2017, I landed in …
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Behind the BugS-layer paper It’s finally out! Our work describing the structure and assembly …
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